Craniopharyngioma Management

Subspecialty: Neuro-oncology

Type: Clinical Summary

Craniopharyngioma are rare, benign but morbid sellar/suprasellar tumours arising from remnants of Rathke’s pouch that produce local mass effects on the optic apparatus, pituitary and hypothalamus; this primer and associated studies synthesize epidemiology, molecular pathogenesis (including divergent drivers for the two subtypes), imaging and histologic features, and contemporary multidisciplinary management including operative strategies and radiotherapy, with emphasis on hypothalamic preservation and functional outcomes. Overview Craniopharyngiomas account for approximately 1.2–4.6% of all in…

Source Papers

Craniopharyngioma (2019)
Childhood craniopharyngioma: hypothalamus-sparing surgery decreases the risk of obesity. (2013)
Craniopharyngioma Resection Among Adults and Children: A Meta-analysis and Systematic Review (2023)