Embryology of the spinal cord
Subspecialty: Spinal dysraphism
Type: Clinical Summary
### Key Findings - Neural tube defects (NTDs) include spina bifida, anencephaly, and encephaloceles, resulting from the failure of neural tube closure during embryonic development. - NTDs are associated with a variety of central nervous system (CNS) and non-neural malformations and exhibit racial, geographic, and seasonal variations in incidence. - The etiology of most non-syndromic NTDs is multifactorial and remains poorly understood, with no Mendelian inheritance patterns identified. - Evidence suggests a strong genetic contribution due to the association of NTDs with single gene defects, he…