Diagnosis and management of meningiomas
Subspecialty: Neuro-oncology
Type: Clinical Summary
Meningioma are the most common primary intracranial tumors and arise from arachnoid cap cells, with biology driven by chromosomal copy number changes (notably loss of 22q and NF2 alterations) and recurrent driver mutations that determine location, histological subtype, and risk of recurrence. This EANO guideline synthesizes diagnostic pathways (imaging, histopathology, and emerging molecular/methylation profiling), indications and modalities for surgery and radiotherapy, and the limited role of systemic therapies, with specific recommendations for follow-up and tissue banking for molecular tes…
Source Papers
- EANO guideline on the diagnosis and management of meningiomas. (2021)